Name Ingredients:
Procapil is a blend of three ingredients: oleanolic acid, apigenin, and biotinyl-GHK. It is marketed as a hair loss treatment, but there is limited evidence to support its use as such.
Key insights:
- The in vitro evidence suggests that procapil’s ingredients have moderate antibacterial, anti-inflammatory, and anti-microbial activity. They also enhance the expression and production of antioxidants, which may be beneficial for hair loss outcomes.
- There is no in vivo evidence that procapil can improve hair loss outcomes. However, there is individual evidence that some of its ingredients can.
- Apigenin has been found to stimulate the growth of hair follicles in ex vivo studies on isolated rat hair follicles to a similar level as those treated with minoxidil.
- Oleanolic acid has also been found to significantly increase hair growth and increase levels of key growth factors involved in hair follicle growth compared to a control group in mice with androgenic alopecia-like hair loss.
- One clinical study was performed on 140 individuals with androgenic alopecia. Over the course of 12 months, patients either applied topical minoxidil twice daily or minoxidil and procapil twice daily (minoxidil and procapil were used on alternating days). Whilst all patients showed improved hair loss, the improvement was greater in the group that used both minoxidil and procapil.
- Our experience tracking members: procapil is not enough by itself to improve hair loss outcomes.
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