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Methylene Blue


Rob (PHH)

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Methylene blue is a compound originally developed as a medical dye. It has recently been stirring up attention due to its potential therapeutic applications beyond its initial purpose, particularly in the realm of age-related concerns such as cognitive and skin health. However, some are now exploring its potential use in hair regrowth.

Key insights:

  • The in vitro and animal studies suggest that methylene blue has antioxidant, mitochondrial-enhancing, and anti-inflammatory properties that could theoretically support hair follicle health. However, these studies were not conducted on human hair follicles.

    • Methylene blue has been shown to reduce oxidative stress, enhance ATP production, and regulate inflammatory pathways, including IL-6 and STAT3 inhibition, which are implicated in certain hair loss conditions.

    • Some in vitro studies suggest that methylene blue promotes skin health by increasing collagen production, wound healing, and scalp thickness, factors that might influence hair regrowth.

  • There is no in vivo or clinical evidence demonstrating that methylene blue improves hair regrowth outcomes. The only hair-related human study tested methylene blue as a storage solution for hair transplants and found it less effective than saline.

  • Our experience tracking members: Methylene blue is not enough by itself to improve hair loss outcome

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