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Hydrocortisone


Rob (PHH)

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Hydrocortisone is a synthetic steroid used to treat alopecia areata due to its anti-inflammatory properties. Applied topically, it may reduce inflammation and itching associated with certain scalp conditions. However, its efficacy in promoting hair growth is limited, and long-term use should be approached cautiously, considering potential side effects.

Key insights:

  • Hydrocortisone treatment may be able to assist in cortisol-imbalance-induced hair loss.
  • The clinical evidence suggests that while hydrocortisone might improve hair regrowth in patients with alopecia areata, it does not perform as well as other corticosteroids.
    • In a comparison study with 41 children with alopecia areata, clobetasole propionate was compared to hydrocortisone:
      • Hydrocortisone showed the greatest decrease in hair loss after 6 weeks of treatment.
      • Clobetasol propionate showed significant improvement in all other time points (weeks 12, 18, and 24).
      • Hydrocortisone treatment reduced scalp surface area by only 4.6% compared to clobetasol propionate, which reduced it by 96.5%.
  • Our experience tracking members: by itself, hydrocortisone alone is not enough to improve hair loss outcomes.
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